Transcenta partner Inhibrx reports 20% ORR in ozekibart colorectal cancer trial

• Transcenta flagged a positive interim update from partner Inhibrx’s Phase 1/2 study of ozekibart combined with chemotherapy in advanced colorectal cancer; the results have already been reported as updated interim data with an April 10, 2026 cutoff.
• The update pointed to tumor shrinkage in some heavily pretreated patients, with broader disease stabilization and side effects described as manageable.
• Inhibrx also filed a U.S. biologics license application in April 2026 seeking approval of ozekibart for conventional chondrosarcoma, a cancer with no approved systemic treatment options.
• Transcenta holds Greater China rights to develop and commercialize ozekibart, prompting it to review regional plans following the U.S. regulatory filing and the colorectal cancer readout.
• Inhibrx plans to meet the FDA in the second half of 2026 to discuss a first-line registrational colorectal cancer trial, alongside potential faster routes in later-line disease.

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