How Is Hologic’s Stock Performance Compared to Other Health Care Equipment Stocks?

With a market cap of $14.3 billion, Hologic, Inc. (HOLX) is a Massachusetts-based medical technology firm, primarily focused on women’s health. The company develops, manufactures, and sells a comprehensive suite of solutions, including molecular diagnostics, medical imaging systems, and surgical devices

Companies worth $10 billion or more are generally described as “large-cap stocks,” and Hologic fits right into that category, with its market cap exceeding this threshold, reflecting its substantial size and influence in the medical instruments & supplies industry. The company benefits from robust innovation, supported by over 7,000 patents, which fuels its proprietary technologies and product differentiation. Its diagnostics segment, particularly in molecular testing, has shown strong growth, positioning Hologic well in the expanding global healthcare market.

However, HOLX shares have retreated 24.5% from their 52-week high of $84.67 touched on Aug. 9, 2024. Meanwhile, HOLX stock has surged 3.2% over the past three months, surpassing the SPDR S&P Health Care Equipment ETF’s (XHE) 4.8% plunge over the same time frame. 

HOLX stock has plummeted 11.3% on a YTD basis and 10.5% over the past 52 weeks, compared to XHE’s 10.6% dip in 2025 and a 6.3% fall over the past year.

The stock has remained consistently below its 200-day moving average since early December last year, but has climbed above its 50-day moving average since late May. 

On May 27, HOLX shares surged more than 14%, leading S&P 500 gainers, after reports emerged that TPG Inc. (TPG) and Blackstone Inc. (BX) made (and were turned down on) a non-binding ~$16 billion takeover bid, valuing the company at $70–$72 per share. The stock’s rally reflected investor optimism and underscored the premium valuation placed on its leadership in women’s health and diagnostic capabilities.

In the competitive healthcare equipment industry, top rival, Align Technology, Inc.’s (ALGN) 13.7% drop on a YTD basis and 25.7% decline over the past year trails HOLX’s losses in the same time frames.

Among the 19 analysts covering the HOLX stock, the consensus rating is a “Moderate Buy.” Its mean price target of $68.27 suggests a 6.7% upside potential from current price levels.