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Opthea Terminates Phase 3 Wet AMD Trials After ShORe Fails To Meet Primary Endpoint, Citing Lack Of Visual Benefit

Benzinga·03/31/2025 06:27:25
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  • ShORe Phase 3 topline results accelerated; trial did not meet primary endpoint of mean change in BCVA from baseline to week 52
  • Opthea and DFA Investors agreed to terminate both COAST and ShORe trials
  • Opthea continues to consider impact of negative trial results under its Development Funding Agreement (DFA) and on the Company as a going concern
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