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Why Silo Pharma Shares Are Trading Higher By Around 52%; Here Are 20 Stocks Moving Premarket

Benzinga·04/07/2026 09:20:34
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Shares of Silo Pharma Inc (NASDAQ:SILO) rose sharply in pre-market trading following a key intellectual property update tied to its PTSD treatment pipeline.

On Monday, the company said the European Patent Office issued a Rule 71(3) communication indicating its intent to grant a patent covering a novel preventative therapy targeting the serotonin 4 (5-HT4) receptor pathway.

Silo Pharma shares jumped 51.8% to $0.54 in pre-market trading.

Here are some other stocks moving in pre-market trading.

Gainers

  • Huachen AI Parking Mgmt Tech Hldg Co Ltd (NASDAQ:HCAI) gained 131.8% to $0.34 in pre-market trading fter the company disclosed a regulatory update tied to its Nasdaq listing compliance.
  • Advanced Biomed Inc. (NASDAQ:ADVB) gained 74% to $7.46 in pre-market trading.
  • Ridgetech Inc (NASDAQ:RDGT) gained 68.8% to $0.031 in pre-market trading. Ridgetech shares dipped more than 25% on Monday after the company announced a 1-for-150 reverse stock split.
  • Cuprina Holdings (Cayman) Ltd (NASDAQ:CUPR) rose 57.4% to $0.62 in pre-market trading after gaining 16% on Monday.
  • Xiao-I Corp (NASDAQ:AIXI) jumped 39.2% to $1.12 in pre-market trading after surging 515% on Monday. Xiao-I recently issued an additional material update on its variable interest entity’s ongoing patent infringement lawsuit against Apple.
  • Organogenesis Holdings Inc (NASDAQ:ORGO) rose 30% to $2.91 in pre-market trading after the company disclosed that it has achieved a primary endpoint in randomized controlled trial of PuraPly®AM.
  • Alignment Healthcare Inc (NASDAQ:ALHC) rose 17.3% to $21.90 in pre-market trading. Shares of health insurance companies traded higher after the Centers for Medicare & Medicaid Services announced a 2.48% rate hike for 2027 Medicare Advantage and Part D programs.
  • Humana Inc (NYSE:HUM) gained 10.8% to $202.44 in pre-market trading after adding 4% on Thursday. The Trump administration on Monday raised the amount it will pay private insurers to run Medicare health plans for seniors, setting rates well above a proposal that had unsettled markets earlier this year.
  • UnitedHealth Group Inc (NYSE:UNH) rose 6.6% to $300.00 in pre-market trading. The Trump administration on Monday raised the amount it will pay private insurers to run Medicare health plans for seniors, setting rates well above a proposal that had unsettled markets earlier this year.

Losers

  • Focus Universal Inc (NASDAQ:FCUV) fell 20.5% to $4.56 in pre-market trading after gaining around 72% on Monday.
  • Profusa Inc (NASDAQ:PFSA) declined 17.8% to $1.52 in pre-market trading. Profusa shares jumped 144% on Monday after the company announced it will acquire the PanOmics multi-omics diagnostics platform from BioInsights LLC for approximately $30 million in stock.
  • Anfield Energy Inc. (NASDAQ:AEC) fell 15.2% to $4.65 in pre-market trading.
  • Biodexa Pharmaceuticals PLC-ADR (NASDAQ:BDRX) dipped 14.5% to $3.31 in pre-market trading after falling 11% on Monday. Biodexa Pharmaceuticals recently announced a partnership with Syngene International for the manufacture of both MTX240 active pharmaceutical ingredient and dosage form.
  • ABVC Biopharma Inc (NASDAQ:ABVC) tumbled 13% to $1.21 in pre-market trading after jumping 28% on Monday.
  • TNL Mediagene (NASDAQ:TNMG) fell 11.2% to $1.71 in pre-market trading. TNL Mediagene recently named Motoko Imada as CEO and appointed Joey Chung as president.
  • SIGA Technologies Inc (NASDAQ:SIGA) shares dipped 10.8% to $4.64 in pre-market trading. SIGA Technologies recently declared a special cash dividend of 60 cents per share.
  • Mesoblast Ltd (NASDAQ:MESO) fell 6.5% to $13.90 in pre-market trading. Mesoblast reported $30.3 million in Ryoncil net sales for March quarter.
  • Clearsign Technologies Corp (NASDAQ:CLIR) dipped 4.2% to $6.65 in pre-market trading after gaining 44% on Monday.
  • Gap Inc (NYSE:GAP) fell 4.1% to $24.33 in pre-market trading after gaining 3% on Monday.

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